PNP-α-D-galactopyranoside, CAS No. 7493-95-0

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7493-95-0

Catalog No. EBD2204873

CAS 7493-95-0

Name PNP-α-D-galactopyranoside

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Basic Information

Synonyms: 4-nitrophenolα-D-galactopyranoside PNP-α-D-galactopyranoside p-nitrophenylα-D-galactopyranoside .alpha.-D-Galactopyranoside,4-nitrophenyl 231-343-6 alpha-D-Galactopyranoside,4-nitrophenyl p-Nitrophenyl.alpha.-D-galactopyranoside 4-nitrophenylalpha-D-galactopyranoside 4-Nitrophenyl-Alpha-D-Galactopyranoside

Molecular Formula: C12H15NO8

Molecular Weight: 301.25

MDL Number: MFCD00065050

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks

Product Description:

4-Nitrophenyl α-D-galactopyranoside is a synthetic chromogenic glycoside derivative. Its chemical structure consists of an α-D-galactopyranose moiety linked via a glycosidic bond to a 4-nitrophenyl group. This compound is a colorless to off-white crystalline powder. This compound is primarily used as a chromogenic substrate for the detection and assay of α-galactosidase enzyme activity. The enzyme cleaves the glycosidic bond, releasing the yellow-colored 4-nitrophenolate ion, which can be quantified spectrophotometrically. It is a critical reagent in biochemical research, clinical diagnostics (e.g., for Fabry disease screening), and microbiology for studying carbohydrate metabolism and identifying specific bacterial or fungal species based on their enzymatic profiles. While its primary identity is as a specialized biochemical reagent, its well-defined structure also makes it a potential building block in synthetic carbohydrate chemistry for constructing more complex glycoconjugates or probes.

Physical Properties

Melting Point: 166-169 °C

Boiling Point: 582.2 °C at 760 mmHg

Flash Point: 305.9 °C

Density: 1.599 g/cm3

Refractivity: 239 ° (C=1, H2O)

Storage: −20°C