(R)-(+)-2-chloropropionic acid, CAS No. 7474-05-7

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7474-05-7

Catalog No. EBD2204879

CAS 7474-05-7

Name (R)-(+)-2-chloropropionic acid

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Basic Information

Synonyms: (R)-(+)-2-Chloropropionicacid (2R)-2-chloropropanoate (2R)-2-chloropropanoicacid R-2-chloro-propionicacid R-2-ChloropropanoicAcid (2R)-chloropropionicacid

Molecular Formula: C3H5ClO2

Molecular Weight: 108.52

MDL Number: MFCD00064204

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Basic Synthetic Reagents > Other Basic Synthetic Reagents

Product Description:

(R)-(+)-2-Chloropropanoic acid is a chiral organic compound characterized by a carboxylic acid group and a chlorine atom on the alpha carbon, with the (R)-configuration. It is a colorless to pale yellow liquid with a pungent odor and is soluble in many organic solvents. This compound serves as a versatile chiral building block in organic synthesis. Its primary application is as a key intermediate in the production of enantiomerically pure agrochemicals, particularly (R)-aryloxypropionate herbicides such as (R)-dichlorprop and (R)-mecoprop. The chiral center is crucial for the herbicidal activity. It is also used in the synthesis of chiral pharmaceuticals and other fine chemicals, where the (R)-2-chloropropanoic acid moiety can be further transformed into various functional groups. Handling requires caution as it is corrosive and can cause severe skin burns and eye damage. It should be stored in a cool, well-ventilated area away from incompatible materials like bases and oxidizing agents.

Physical Properties

Melting Point: -12°C

Boiling Point: 185-188 °C(lit.)

Flash Point: 101 °C

Density: 1.258 g/mL at 20 °C(lit.)

Refractivity: n20/D 1.4345(lit.)

Storage: −20°C

Safety Information

Packing Level: III

Hazard Category: 8

Transport Codes: 2511

Analytical Data

Appearance: colourless oil