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    74420-02-3

    Catalog No. EBD47855

    CAS 74420-02-3

    Name 4-hydroxy-7-azaindole

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    Basic Information

    Synonyms: 4-hydroxy-7-azaindole 1H-pyrrolo[2,3-b]pyridin-4-ol

    Molecular Formula: C7H6N2O

    Molecular Weight: 134.14

    MDL Number: MFCD08272229

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    4-Hydroxy-7-azaindole is a heterocyclic organic compound featuring an indole core where one nitrogen atom is replaced at the 7-position (aza-substitution) and a hydroxyl group is attached at the 4-position. It serves as a versatile and privileged scaffold in medicinal chemistry. Its primary application is as a key synthetic intermediate or building block in the development of pharmaceutical agents. The 7-azaindole moiety is a bioisostere of purine and is commonly found in compounds targeting protein kinases, making it highly valuable for the discovery of kinase inhibitors used in oncology and other therapeutic areas. The presence of both hydrogen bond donor (OH) and acceptor (N) sites allows for specific interactions with biological targets. This compound is commercially available from suppliers specializing in advanced pharmaceutical intermediates and heterocyclic building blocks for drug discovery programs.
    Physical Properties

    Density: 1.434 g/cm3

    mg g kg ml l t