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    737751-95-0

    Catalog No. EBD52742

    CAS 737751-95-0

    Name (R)-3-Amino-3-(2-bromophenyl)propanoic acid

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    Basic Information

    Synonyms: (R)-3-Amino-3-(2-bromophenyl)propanoicacid D-3-Amino-3-(2-bromophenyl)-propionicacid (R)-3-Amino-3-(2-bromophenyl)-propionicacid (R)-3-Amino-3-(2-bromo-phenyl)-propionicacid

    Molecular Formula: C9H10BrNO2

    Molecular Weight: 244.09

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    D-3-Amino-3-(2-bromophenyl)propanoic acid is a chiral non-natural amino acid derivative featuring a 2-bromophenyl substituent on the beta-carbon of an alanine backbone. It serves as a crucial chiral building block in pharmaceutical research and development. This compound is primarily utilized as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders. Its structure, containing both an amino group and a carboxylic acid, allows for versatile incorporation into peptide-like structures or as a scaffold for further functionalization. The presence of the bromine atom on the phenyl ring provides a handle for further cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling the construction of more complex molecular architectures. As a chiral synthon, it is valuable for introducing stereochemical complexity into drug candidates. It is commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies and the preparation of potential drug molecules.
    Physical Properties
    mg g kg ml l t