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    730980-59-3

    Catalog No. EBD2221063

    CAS 730980-59-3

    Name (R)-Chroman-4-amine hydrochloride

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    Basic Information

    Synonyms: (R)-Chroman-4-aminehydrochloride

    Molecular Formula: C9H12ClNO

    Molecular Weight: 185.65

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (4R)-3,4-Dihydro-2H-1-benzopyran-4-amine hydrochloride is a chiral amine derivative featuring a benzopyran (chromane) scaffold. This compound is characterized by its specific (4R) stereochemistry and exists as a hydrochloride salt, enhancing its stability and solubility for synthetic applications. This chiral chromane amine serves as a crucial intermediate in pharmaceutical research and development. Its primary application is in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular disorders. The scaffold is a privileged structure found in several drug candidates and bioactive molecules due to its favorable pharmacokinetic properties. As a building block, it provides both a rigid, aromatic benzopyran core and a handle for further functionalization via the amine group. Its chirality makes it valuable for constructing enantiomerically pure compounds. It is typically handled under standard laboratory conditions for amine hydrochlorides, requiring protection from moisture.
    Physical Properties
    mg g kg ml l t