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    724787-35-3

    Catalog No. EBD3678231

    CAS 724787-35-3

    Name Carbamic acid,N-[(3S,4R)-3-hydroxy-4-piperidinyl]-, 1,1-dimethylethyl ester

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    Basic Information

    Synonyms: Carbamicacid,[(3S,4R)-3-hydroxy-4-piperidinyl]-,1,1-dimethylethylester(9CI) (3S,4R)-(3-Hydroxypiperidin-4-yl)carbamicacidtert-butylester Carbamicacid,N-[(3S,4R)-3-hydroxy-4-piperidinyl]-,1,1-dimethylethylester

    Molecular Formula: C10H20N2O3

    Molecular Weight: 216.28

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates

    Product Description:
    Carbamic acid, N-[(3S,4R)-3-hydroxy-4-piperidinyl]-, 1,1-dimethylethyl ester is a chiral piperidine derivative featuring both a hydroxyl group and a tert-butoxycarbonyl (Boc) protected amine. This specific stereochemistry ((3S,4R)) is crucial for its intended applications. This compound is primarily utilized as a key chiral building block in pharmaceutical research and development. It serves as a versatile intermediate for the synthesis of more complex molecules, particularly those targeting the central nervous system. Its structure is integral to the preparation of potential drug candidates, including inhibitors of enzymes like dipeptidyl peptidase IV (DPP-4) for diabetes treatment and other therapeutic agents where the piperidine scaffold is pharmacologically relevant. The Boc-protected amine provides a handle for selective deprotection and further functionalization under mild conditions, making it a valuable and protected synthon in multi-step organic synthesis focused on medicinal chemistry.
    Physical Properties
    mg g kg ml l t