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    7242-92-4

    Catalog No. EBD3329266

    CAS 7242-92-4

    Name rac-exo-bicyclo[2.2.1]hept-2-ylamine

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    Basic Information

    Synonyms: rac-exo-bicyclo[2.2.1]hept-2-ylamine exo-2-aminonorbornane exo-2-bornanamine dioxoosmium (1S,2S,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-amine

    Molecular Formula: C7H13N

    Molecular Weight: 111.18

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    Exo-2-Aminonorbornane is a chiral bicyclic amine characterized by its rigid norbornane skeleton and an exo-configured amino group. This structural rigidity and defined stereochemistry make it a valuable scaffold in organic synthesis and medicinal chemistry. Its primary application is as a chiral building block or intermediate in pharmaceutical research. The constrained geometry of the norbornane framework is utilized to influence the conformation and biological activity of target molecules. It serves as a key precursor in the synthesis of various pharmacologically active compounds, including potential drug candidates targeting the central nervous system and other therapeutic areas. The exo-amine functionality is readily amenable to further derivatization. As a secondary amine with a unique three-dimensional structure, it is also employed in academic and industrial research as a ligand precursor or as a model compound for studying stereoelectronic effects and reaction mechanisms.
    Physical Properties

    Boiling Point: 669.586 °C at 760 mmHg

    Flash Point: 358.753 °C

    Density: 1.292 g/cm3

    mg g kg ml l t