Methyl-2,3-O-isopropylidene-D-ribofuranoside, CAS No. 72402-14-3

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72402-14-3

Catalog No. EBD48307

CAS 72402-14-3

Name Methyl-2,3-O-isopropylidene-D-ribofuranoside

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Basic Information

Synonyms: [(3aR,4R,6aR)-6-methoxy-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]methanol C.I.60752 4-[(1-Amino-9,10-dihydro-4-hydroxy-9,10-dioxo-2-anthracenyl)oxy]-N-(3-ethoxypropyl)-benzenesulfonamide Methyl-2,3-O-isopropylidene-D-ribofuranoside

Molecular Formula: C9H16O5

Molecular Weight: 204.22

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks

Product Description:

Methyl-2,3-O-isopropylidene-D-ribofuranoside is a protected ribose derivative featuring an isopropylidene acetal group at the 2,3-diol position and a methyl glycoside at the anomeric carbon. This structure serves as a key synthetic intermediate in nucleoside chemistry, enabling selective modifications at the 5бп-hydroxyl group or the base moiety without interference from the cis-diol. It is widely utilized in the preparation of antiviral and anticancer nucleoside analogs, such as those targeting RNA viruses or DNA polymerases. Additionally, it functions as a building block for oligonucleotide synthesis and carbohydrate-based drug discovery. The compound is stable under standard storage conditions and is typically handled as a colorless to pale yellow oil or crystalline solid.

Physical Properties