D-1,2,3,4-tetrahydronorharmane-3-carboxylic acid, CAS No. 72002-54-1

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72002-54-1

Catalog No. EBD2293834

CAS 72002-54-1

Name D-1,2,3,4-tetrahydronorharmane-3-carboxylic acid

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Basic Information

Synonyms: 1H-Pyrido[3,4-b]indole-3-carboxylicacid,2,3,4,9-tetrahydro-,(3R)- D-1,2,3,4-tetrahydronorharmane-3-carboxylicacid 1H-Pyrido[3,4-b]indole-3-carboxylicacid,2,3,4,9-tetrahydro-,(R)- (3R)-1,2,3,4-Tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylicacid (R)-1,2,3,4-Tetrahydro-3-carboxy-2-carboline D-1,2,3,4-Tetrahydro-3-carboxy-2-carboline H-D-Tpi-OH

Molecular Formula: C12H12N2O2

Molecular Weight: 216.24

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

Product Description:

D-1,2,3,4-Tetrahydronorharmane-3-carboxylic acid is a chiral, heterocyclic amino acid derivative. Its structure features a tetrahydro-β-carboline core, which is a privileged scaffold in medicinal chemistry, with a carboxylic acid substituent at the 3-position. This compound is the D-enantiomer of the corresponding amino acid. This molecule serves as a key chiral building block and intermediate in the synthesis of more complex pharmaceutical agents. The tetrahydro-β-carboline moiety is a common structural motif found in numerous biologically active compounds, including those with neurological and psychotropic activities. Its primary application lies in research and development for constructing potential drug candidates, particularly in the areas of central nervous system (CNS) disorders. As a non-proteinogenic amino acid derivative, it is also relevant in biochemical and peptide mimetic research. It is typically handled as a high-purity research chemical for synthetic and pharmacological studies.

Physical Properties

Boiling Point: 485 °C at 760 mmHg

Flash Point: 247.1 °C

Density: 1.377 g/cm3