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    72002-30-3

    Catalog No. EBD26068

    CAS 72002-30-3

    Name (R)-6-Oxopiperidine-2-carboxylic acid

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    Basic Information

    Synonyms: (2R)-6-oxopiperidine-2-carboxylicacid 2-Piperidinecarboxylicacid,6-oxo-,(2R)- (R)-6-Oxo-piperidine-2-carboxylicacid (R)-6-Oxopiperidine-2-carboxylicacid

    Molecular Formula: C6H9NO3

    Molecular Weight: 143.14

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

    Product Description:
    (R)-6-Oxopiperidine-2-carboxylic acid is a chiral heterocyclic compound featuring a piperidine ring with a carboxylic acid group at the 2-position and a ketone at the 6-position. It is a derivative of the non-proteinogenic amino acid pipecolic acid (piperidine-2-carboxylic acid). The compound is characterized by its (R)-configuration, making it a valuable chiral building block. This compound serves as a crucial intermediate in the synthesis of various pharmaceuticals and bioactive molecules. Its primary application is in the production of peptide-mimetic drugs and enzyme inhibitors, where the constrained piperidine ring structure is used to modulate biological activity and metabolic stability. It is notably employed in the research and development of renin inhibitors and other protease-targeting therapeutics. As a derivative of pipecolic acid, it also finds relevance in biochemical studies related to plant defense signaling and lysine metabolism. The compound is typically handled as a solid and requires storage under cool, dry conditions.
    Physical Properties

    Boiling Point: 437°C at 760 mmHg

    Flash Point: 218.1°C

    Density: 1.286g/cm3

    mg g kg ml l t