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    71486-53-8

    Catalog No. EBD1616622

    CAS 71486-53-8

    Name methyl 4-oxopiperidine-3-carboxylate hydrochloride

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    Basic Information

    Synonyms: Methyl4-oxo-3-piperidinecarboxylatehydrochloride 4-piperidine-3-carboxylicacidmethylketonehydrochloride 3-Carbomethoxy-4-piperidonehydrochloride Methyl4-oxo-3-piperidinecarboxylateHCl methyl4-oxopiperidine-3-carboxylatehydrochloride

    Molecular Formula: C7H12ClNO3

    Molecular Weight: 193.63

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    Methyl 4-oxopiperidine-3-carboxylate hydrochloride is a heterocyclic organic compound featuring a piperidine ring substituted with a methyl ester and a ketone group at the 3- and 4-positions, respectively, and exists as a hydrochloride salt. It serves as a versatile and crucial synthetic building block in medicinal chemistry. Its primary application is as a key intermediate in the synthesis of various pharmaceutical compounds. The molecule's structure, containing both a reactive ketone and an ester group on a piperidine scaffold, makes it a valuable precursor for constructing more complex heterocyclic systems and drug candidates. It is notably used in the research and development of central nervous system (CNS) active agents and other bioactive molecules. As a bifunctional synthon, it is widely utilized in academic and industrial research laboratories for constructing piperidine-based libraries and exploring structure-activity relationships (SAR). Handling requires standard laboratory precautions for organic salts.
    Physical Properties

    Melting Point: ~175 °C (dec.)(lit.)

    Boiling Point: 249.4 °C at 760 mmHg

    Flash Point: 104.6 °C

    Analytical Data

    Appearance: white or cream-colored powder

    mg g kg ml l t