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    70882-66-5

    Catalog No. EBD41450

    CAS 70882-66-5

    Name N-alpha-Cbz-D-2-4-diaminobutanoic acid

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    Basic Information

    Synonyms: Z-D-Dab-OH N-Alpha-Cbz-D-2-4-DiaminobutanoicAcid N-alpha-Benzyloxycarbonyl-D-2,4-diaminobutyricacid

    Molecular Formula: C12H16N2O4

    Molecular Weight: 252.27

    MDL Number: MFCD00237344

    Categories: Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    N-alpha-Benzyloxycarbonyl-D-2,4-diaminobutyric acid is a protected derivative of the non-proteinogenic amino acid D-2,4-diaminobutyric acid (D-Dab). Its structure features a benzyloxycarbonyl (Cbz or Z) group protecting the alpha-amino group, leaving the side-chain amino group available for further chemical modification. This compound serves as a crucial chiral building block in the synthesis of peptides and peptidomimetics. The D-configuration and the presence of two amino groups make it valuable for introducing specific structural motifs, such as turns or bridges, and for creating constrained peptide analogs with potential biological activity. It is particularly important in medicinal chemistry research for developing novel therapeutic agents, including antimicrobial peptides and enzyme inhibitors. As a specialty amino acid derivative, it is primarily used in research-scale solid-phase and solution-phase peptide synthesis. Its handling requires standard precautions for laboratory chemicals.
    Physical Properties
    mg g kg ml l t