Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    704-91-6

    Catalog No. EBD48406

    CAS 704-91-6

    Name 1H-Indazole-6-carboxylic acid

    Get Quote
    Basic Information

    Synonyms: 1H-indazole-6-carboxylic acid 6-(1H)Indazolecarboxylicacid 1H-Indazole-6-carboxylicacid

    Molecular Formula: C8H6N2O2

    Molecular Weight: 162.15

    Categories: Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    1H-Indazole-6-carboxylic acid is a heterocyclic compound featuring an indazole core with a carboxylic acid substituent at the 6-position. Its molecular formula is C8H6N2O2, and it serves as a key building block in medicinal chemistry. This compound is primarily utilized as a synthetic intermediate for the development of small-molecule drugs, particularly in the design of kinase inhibitors and other therapeutic agents targeting cancer, inflammation, and neurological disorders. The indazole scaffold is known for its ability to interact with biological targets through hydrogen bonding and ж╨-stacking, while the carboxylic acid group enables further functionalization or salt formation. Due to its structural versatility, 1H-Indazole-6-carboxylic acid is widely employed in drug discovery programs as a core fragment for lead optimization. It is also used in the synthesis of agrochemicals and specialty chemicals, though its primary application remains in pharmaceutical research.
    Physical Properties

    Melting Point: 302-307 °C

    Boiling Point: 443.749 °C at 760 mmHg

    Flash Point: 222.172 °C

    Density: 1.507 g/cm3

    mg g kg ml l t