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    7013-07-2

    Catalog No. EBD3961

    CAS 7013-07-2

    Name (R)-(-)-4-Amino-3-hydroxybutanoic acid

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    Basic Information

    Synonyms: (3R)-4-Amino-3-hydroxybutanoicacid butanoicacid,4-amino-3-hydroxy-,(3R)- (R)-4-Amino-3-Hydroxy-ButyricAcid (R)-(-)-4-Amino-3-hydroxybutanoicacid

    Molecular Formula: C4H9NO3

    Molecular Weight: 119.12

    MDL Number: MFCD02262047

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

    Product Description:
    (R)-(-)-4-Amino-3-hydroxybutanoic acid is a chiral, non-proteinogenic amino acid derivative. It is structurally characterized by a four-carbon backbone featuring both an amino group and a hydroxyl group on adjacent carbon atoms, with the stereocenter at the 3-position. This compound is a key building block in the synthesis of biologically active molecules. Its primary and most significant application is as a crucial chiral intermediate in the pharmaceutical industry. It serves as a core structural unit for the synthesis of (R)-Carnitine, an essential nutrient involved in fatty acid metabolism. Furthermore, it is a vital precursor in the production of (R)-4-Amino-3-hydroxybutyric acid (GABOB), a naturally occurring inhibitory neurotransmitter analog with potential therapeutic applications for neurological disorders. Its chirality is critical for biological activity. The compound is also utilized in the synthesis of other pharmacologically relevant targets and serves as a valuable chiral synthon in asymmetric synthesis. It is typically handled as a solid and requires storage under appropriate conditions to maintain stability.
    Physical Properties

    Boiling Point: 374.5 °C at 760 mmHg

    Flash Point: 180.3 °C

    Density: 1.312 g/cm3

    mg g kg ml l t