5-Fluoro-1-indanone, CAS No. 700-84-5

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

700-84-5

Catalog No. EBD41717

CAS 700-84-5

Name 5-Fluoro-1-indanone

Get Quote

Basic Information

Synonyms: 5-Fluoro-indan-1-one 5-Fluoro-1-indanone 5-fiuoro-1-indonone 5-flouro-1-indanone 5-fluoro-1-indonone 5-fluoro-l-indonone

Molecular Formula: C9H7FO

Molecular Weight: 150.15

MDL Number: MFCD00041031

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Aldehydes and Ketones

Product Description:

5-Fluoro-1-indanone is an organic compound featuring a fused bicyclic structure consisting of a benzene ring and a five-membered ketone ring, with a fluorine substituent at the 5-position. It is a solid at room temperature and serves as a versatile fluorinated building block in synthetic chemistry. This compound is primarily utilized as a key intermediate in pharmaceutical research and development. Its indanone core, functionalized with a ketone group and a fluorine atom, makes it a valuable precursor for synthesizing more complex bioactive molecules. It is notably employed in the synthesis of compounds targeting various therapeutic areas, including central nervous system disorders. As a fluorinated aromatic ketone, 5-Fluoro-1-indanone is a valuable synthon in organic synthesis, enabling further functionalization through reactions at the carbonyl group or the aromatic ring. Its incorporation into target structures can modulate the lipophilicity, metabolic stability, and binding affinity of the final drug candidates.

Physical Properties

Melting Point: 38-40 °C(lit.)

Boiling Point: 113-114 °C(lit.)

Flash Point: 113 °C

Density: 1.216 g/mL at 25 °C(lit.)

Solubility: insoluble

Storage: Refrigerator

Analytical Data

Appearance: white to yellowish crystalline low melting solid