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    6982-42-9

    Catalog No. EBD3722972

    CAS 6982-42-9

    Name (1R,3S)-rel-3-amino-Cyclohexanol

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    Basic Information

    Synonyms: (1R,3S)-rel-3-amino-Cyclohexanol Cyclohexanol,3-amino-,(1R,3S)-rel- Cyclohexanol,3-amino-,cis-(8CI) cis-3-Aminocyclohexanol cis-3-Hydroxycyclohexylamine

    Molecular Formula: C6H13NO

    Molecular Weight: 115.17

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (1R,3S)-rel-3-Aminocyclohexanol is a chiral amino alcohol compound with a cyclohexane backbone. It exists as a mixture of diastereomers (rel configuration) and serves as a versatile chiral building block in organic synthesis. Its structure combines both an amino group and a hydroxyl group on a six-membered ring, making it a valuable scaffold for constructing more complex molecules. This compound is primarily utilized as a key chiral intermediate in the pharmaceutical industry. It is employed in the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting the central nervous system and other therapeutic areas where the introduction of a chiral, functionalized cyclohexane motif is crucial for biological activity. The amino and hydroxyl groups provide handles for further chemical modifications and derivatizations. As a bifunctional chiral synthon, it is also relevant in asymmetric synthesis and catalysis research. Its availability in the rel form makes it a starting point for the preparation of enantiomerically pure materials through resolution or asymmetric synthesis techniques.
    Physical Properties
    mg g kg ml l t