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    69684-69-1

    Catalog No. EBD28605

    CAS 69684-69-1

    Name (S)-Azetidine-2-carboxylic acid methyl ester hydrochloride

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    Basic Information

    Synonyms: methyl(2S)-azetidine-2-carboxylatehydrochloride Methyl(2S)-azetidine-2-carboxylatehydrochloride(1:1) (S)-Azetidine-2-CarboxylicAcidMethylEsterHydrochloride

    Molecular Formula: C5H10ClNO2

    Molecular Weight: 151.59

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    Methyl 2-azetidinecarboxylate hydrochloride is a hydrochloride salt of a heterocyclic compound featuring an azetidine ring, a four-membered nitrogen-containing ring system. It serves as a versatile and important building block in organic synthesis, particularly in medicinal chemistry. Its primary application is as a key intermediate in the synthesis of various pharmaceutical compounds. The azetidine ring is a valuable scaffold for drug discovery due to its conformational constraints and potential to improve metabolic stability and binding affinity. This specific ester derivative is commonly used to introduce the azetidine moiety into target molecules, often after further functionalization or deprotection steps. It is a crucial precursor in the synthesis of beta-lactamase inhibitors and other bioactive molecules targeting bacterial infections. As a protected form of 2-azetidinecarboxylic acid, it facilitates handling and specific chemical transformations. The compound is typically used in research and development settings for constructing novel chemical entities with potential therapeutic applications.
    Physical Properties

    Boiling Point: 190.9°C at 760 mmHg

    Flash Point: 69.3°C

    mg g kg ml l t