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    696-60-6

    Catalog No. EBD2261650

    CAS 696-60-6

    Name (4-HYDROXYPHENYL)METHANAMINIUM BROMIDE

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    Basic Information

    Synonyms: 4-(Aminomethyl)phenol 4-Hydroxybenzylamine p-Hydroxybenzylamine 4-(aminomethyl)phenolhydrobromide

    Molecular Formula: C7H9NO

    Molecular Weight: 123.15

    MDL Number: MFCD00870499

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Other Pharmaceutical Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    4-(Aminomethyl)phenol is an organic compound featuring both a phenolic hydroxyl group and a primary amino group attached to a benzene ring. This bifunctional structure makes it a versatile building block in organic synthesis. Its primary application is as a key intermediate in the pharmaceutical industry. It serves as a crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those belonging to the class of β-adrenergic blocking agents (beta-blockers). For example, it is a fundamental starting material for the production of drugs like atenolol and related compounds used in the treatment of cardiovascular diseases such as hypertension and angina pectoris. Beyond its pharmaceutical use, this compound is also employed in the synthesis of certain dyes, polymers, and as a cross-linking agent due to its reactive functional groups. It requires careful handling as it can be irritating to the skin, eyes, and respiratory system.
    Physical Properties

    Melting Point: 123-128 °C

    Boiling Point: 262.4 °C at 760 mmHg

    Flash Point: 112.5 °C

    Density: 1.141 g/cm3

    Analytical Data

    Appearance: Light green solid

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