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    68716-49-4

    Catalog No. EBD579691

    CAS 68716-49-4

    Name 4-bromophenylboronic acid pinacol ester

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    Basic Information

    Synonyms: 4-Bromophenylboronicacidpinacolester 2-(4-Bromo-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane 2-(4-bromophenyl)-4,4,5,5-tetramethyl-[1,3,2]-dioxaborolane 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)bromobenzene 2-(4-bromophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 2-(4-bromophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane p-bromophenylboronicacidpinacolester

    Molecular Formula: C12H16BBrO2

    Molecular Weight: 282.97

    Categories: Synthetic Chemistry > Organic Building Blocks > Boronic Acids and Boronic Esters Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    4-Bromophenylboronic acid pinacol ester is an organoboron compound featuring a bromine atom and a boronic ester group on a benzene ring. The pinacol ester group serves as a protecting group for the boronic acid functionality, significantly enhancing its stability, crystallinity, and handling properties compared to the free boronic acid. This makes it a shelf-stable, air- and moisture-tolerant solid, ideal for storage and use in synthetic chemistry. This compound is a versatile and fundamental building block in modern organic synthesis, particularly in transition-metal-catalyzed cross-coupling reactions. The bromine atom acts as an excellent electrophilic site for reactions like Suzuki-Miyaura coupling, where the boronic ester moiety serves as the nucleophilic partner. This dual functionality allows for the efficient construction of biaryl and other conjugated systems, which are core structures in pharmaceuticals, agrochemicals, and advanced materials like organic semiconductors and liquid crystals. Its primary role is as a key synthetic intermediate in research and development laboratories.
    Physical Properties

    Storage: −20°C

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