(1S,2S)-2-Aminocyclopentanol hydrochloride, CAS No. 68327-04-8

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68327-04-8

Catalog No. EBD2220849

CAS 68327-04-8

Name (1S,2S)-2-Aminocyclopentanol hydrochloride

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Basic Information

Synonyms: (1S,2S)-2-Aminocyclopentanolhydrochloride Trans-(1S,2S)-2-Amino-CyclopentanolHydrochloride (1S,2S)-2-aminocyclopentanolchlorhydrate (1S,2S)-2-Aminocyclopentanolhydrochloride(1:1) (1S,2S)-2-Aminocyclopentanolhydrochlorid Cyclopentanol,2-amino-,(1S,2S)-,hydrochloride(1:1) (1S,2S)-Trans-2-AminocyclopentanolHydrochloride Trans-(1S,2S)-2-aimino-cyclopentanolHydrochloride

Molecular Formula: C5H12ClNO

Molecular Weight: 137.61

MDL Number: MFCD07370092

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

Trans-(1S,2S)-2-Aminocyclopentanol hydrochloride is a chiral organic compound featuring both an amino group and a hydroxyl group on a cyclopentane ring in a trans configuration with defined (1S,2S) stereochemistry. It is typically supplied as a hydrochloride salt to enhance stability and handling properties. This compound serves as a valuable chiral building block in pharmaceutical synthesis. Its rigid, functionalized cyclopentane scaffold and defined stereochemistry make it a key intermediate for constructing complex molecules with specific three-dimensional architectures. It is particularly useful in the synthesis of antiviral agents, enzyme inhibitors, and other bioactive compounds where the spatial arrangement of functional groups is critical for biological activity. As a bifunctional chiral synthon, it is employed in medicinal chemistry research and process development. Its applications leverage both the nucleophilic amino group and the hydroxyl group for further chemical transformations, enabling the introduction of the chiral cyclopentane moiety into target drug candidates.

Physical Properties

Boiling Point: 220.9 °C at 760 mmHg

Flash Point: 87.4 °C