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    672309-94-3

    Catalog No. EBD17965

    CAS 672309-94-3

    Name (R)-2-Cbz-aminobutane-1,4-diol

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    Basic Information

    Synonyms: (R)-2-Cbz-aminobutane-1,4-diol benzyl[(1R)-3-hydroxy-1-(hydroxymethyl)propyl]carbamate

    Molecular Formula: C12H17NO4

    Molecular Weight: 239.27

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (R)-2-Cbz-aminobutane-1,4-diol is a chiral organic compound featuring a 1,4-diol backbone with a Cbz-protected amino group at the chiral center. Its molecular formula is C12H17NO4, and it is characterized by the presence of both amine and hydroxyl functional groups, making it a versatile building block for synthetic chemistry. This compound is primarily utilized as a key chiral intermediate in the synthesis of pharmaceutical agents. Its structure, containing a protected amine and two hydroxyl groups, allows for selective functionalization and incorporation into more complex molecular architectures. It is particularly valuable in the preparation of active pharmaceutical ingredients (APIs) and other bioactive molecules where the (R)-configuration is required for biological activity or specific interaction. As a chiral synthon, it serves as a crucial starting material or intermediate in medicinal chemistry research and development. The Cbz (carboxybenzyl) protecting group on the amine is stable under many reaction conditions and can be selectively removed when needed, facilitating multi-step synthetic sequences.
    Physical Properties

    Boiling Point: 461 °C at 760 mmHg

    Flash Point: 232.6 °C

    Density: 1.22 g/cm3

    mg g kg ml l t