(R)-2-Oxotetrahydrofuran-3-ylcarbamic acid tert-butyl ester is a chiral heterocyclic compound featuring a γ-lactam (2-oxotetrahydrofuran) ring system with a tert-butoxycarbonyl (Boc)-protected amine group at the 3-position. Its molecular formula is C9H15NO4, and it is characterized by its specific (R)-configuration at the stereogenic center. This compound serves as a crucial chiral building block in pharmaceutical synthesis. Its primary application is as a key intermediate in the production of various active pharmaceutical ingredients (APIs), particularly those containing the γ-lactam or proline-like structural motifs. The Boc-protected amine and the reactive lactam carbonyl make it a versatile precursor for constructing more complex molecules via further functionalization and ring-opening reactions. As a specialty intermediate, it is not a commodity chemical but is supplied for research and development purposes in medicinal chemistry. Standard safety precautions for handling organic compounds should be observed, including the use of personal protective equipment in a well-ventilated laboratory environment.