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    6698-26-6

    Catalog No. EBD89620

    CAS 6698-26-6

    Name (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyloxolan-3-ol

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    Basic Information

    Synonyms: 2',5'-dideoxyadenosine adenosine,2',5'-dideoxy- (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyl-tetrahydrofuran-3-ol (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyloxolan-3-ol

    Molecular Formula: C10H13N5O2

    Molecular Weight: 235.24

    Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates

    Product Description:
    2,5-Dideoxyadenosine is a synthetic nucleoside analog derived from adenosine. Its chemical structure features a deoxyribose sugar moiety that lacks hydroxyl groups at both the 2' and 5' positions, distinguishing it from natural nucleosides. This modification significantly alters its biochemical properties and interactions with enzymes. This compound serves as a crucial biochemical tool and research reagent. It is primarily used as a potent and selective inhibitor of adenylate cyclase, a key enzyme in the cyclic AMP (cAMP) signaling pathway. By inhibiting cAMP production, it is employed in pharmacological and cell biology studies to investigate the role of this second messenger in various physiological processes, including cardiac function, hormone action, and neurotransmission. Its utility extends to the synthesis of more complex nucleoside analogs for medicinal chemistry research. As a modified nucleoside, 2,5-Dideoxyadenosine is handled as a research chemical for laboratory use only. It is not intended for diagnostic or therapeutic applications.
    Physical Properties

    Color: white

    Boiling Point: 547 °C at 760 mmHg

    Flash Point: 284.6 °C

    Density: 1.77 g/cm3

    Solubility: DMSO: soluble

    Analytical Data

    Appearance: White Solid

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