4-Chlorophenyl cyclopropyl ketone, CAS No. 6640-25-1

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6640-25-1

Catalog No. EBD12528

CAS 6640-25-1

Name 4-Chlorophenyl cyclopropyl ketone

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Basic Information

Synonyms: (4-Chlorophenyl)cyclopropylmethanone (4-Chlorobenzoyl)cyclopropane 4-Chlorophenylcyclopropylketone

Molecular Formula: C10H9ClO

Molecular Weight: 180.63

MDL Number: MFCD00001295

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Aldehydes and Ketones

Product Description:

4-Chlorophenyl cyclopropyl ketone is an organic compound featuring a cyclopropyl ketone group attached to a 4-chlorophenyl ring. It serves as a versatile and valuable synthetic building block in organic chemistry. The presence of both the reactive ketone carbonyl and the aromatic chloride provides two distinct handles for further chemical transformations, such as nucleophilic addition, reduction, or cross-coupling reactions. Its primary application is in medicinal chemistry and pharmaceutical research as a key intermediate for the synthesis of more complex molecules. For instance, it has been utilized in the development of compounds with potential biological activity. The cyclopropyl group is a privileged structural motif often incorporated to modulate the physicochemical and metabolic properties of drug candidates. This compound is typically used in laboratory-scale synthesis and is not a final active pharmaceutical ingredient (API) itself.

Physical Properties

Melting Point: 29-31 °C(lit.)

Boiling Point: 135-137°C 10mm

Flash Point: >113 °C

Density: 1.16

Refractivity: n20/D 1.5718(lit.)

Analytical Data

Appearance: Clear yellowish liquid after melting