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    6628-04-2

    Catalog No. EBD31383

    CAS 6628-04-2

    Name 2-Methylquinolin-4-amine

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    Basic Information

    Synonyms: 2-Methylquinolin-4-amine 4-aminoquinaldine 4-amino-2-methylquinoline 2-methylquinolin-4-ylamine

    Molecular Formula: C10H10N2

    Molecular Weight: 158.2

    MDL Number: MFCD00006759

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    4-Aminoquinaldine is an organic compound featuring a quinoline core structure substituted with an amino group at the 4-position and a methyl group at the 2-position. It is a solid with the molecular formula C₁₀H₁₀N₂ and serves as a versatile nitrogen-containing heterocyclic building block. Its primary industrial significance lies in its role as a key pharmaceutical intermediate. It is notably used in the synthesis of various bioactive molecules, including certain antimalarial agents and other therapeutic compounds that leverage the quinoline pharmacophore. The amino group provides a reactive handle for further functionalization, making it valuable for constructing more complex molecular architectures in medicinal chemistry. Beyond its pharmaceutical applications, 4-aminoquinaldine is also employed in research as a precursor for dyes, ligands in coordination chemistry, and as a model compound in heterocyclic chemistry studies. It requires careful handling as it may be harmful if swallowed or inhaled and can cause skin and eye irritation.
    Physical Properties

    Melting Point: 162-166 °C(lit.)

    Boiling Point: 333 °C(lit.)

    Flash Point: 333°C

    Density: 1.169 g/cm3

    Analytical Data

    Appearance: Slightly beige to light yellow powder

    mg g kg ml l t