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    65896-11-9

    Catalog No. EBD34475

    CAS 65896-11-9

    Name 2-Bromo-6-fluoroaniline

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    Basic Information

    Synonyms: 6-BROMO-2-FLUOROANILINE 2-Bromo-6-fluoroaniline 2-bromo-6-fluorobenzenamine

    Molecular Formula: C6H5BrFN

    Molecular Weight: 190.01

    MDL Number: MFCD01310982

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    2-Bromo-6-fluoroaniline is an organic compound featuring both bromine and fluorine substituents on an aniline ring. It is a halogenated aromatic amine with the molecular formula C6H5BrFN. This compound is typically a solid at room temperature and serves as a versatile building block in synthetic chemistry. Its primary application is as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. The presence of both bromine and fluorine atoms, along with the reactive amino group, makes it a valuable precursor for constructing heterocyclic systems and for introducing specific substitution patterns via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig). It is frequently used in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. As a bifunctional synthon, it allows for sequential functionalization, enabling chemists to build diverse molecular architectures. Standard safety precautions for handling halogenated aromatic amines should be observed, including the use of personal protective equipment due to potential toxicity and skin/eye irritation.
    Physical Properties

    Boiling Point: 211 °C at 760 mmHg

    Flash Point: 81.4 °C

    Density: 1.674 g/mL at 20 °C(lit.)

    Refractivity: n20/D 1.582(lit.)

    Analytical Data

    Appearance: Clear yellow to brown liquid

    mg g kg ml l t