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    65058-23-3

    Catalog No. EBD3313937

    CAS 65058-23-3

    Name (R)-2-(2-Thienyl)-glycine

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    Basic Information

    Synonyms: (R)-2-(2-Thienyl)-glycine L-A-(2-thienyl)glycine

    Molecular Formula: C6H7NO2S

    Molecular Weight: 157.19

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Medicinal Chemistry > Biochemicals and Life Science Reagents > Amino Acids and Derivatives

    Product Description:
    (R)-2-(2-Thienyl)glycine, with CAS number 65058-23-3, is a non-proteinogenic amino acid derivative. Its structure features a glycine backbone where one hydrogen atom on the alpha-carbon is substituted with a 2-thienyl group, and it possesses a specific (R)-configuration at the chiral center. This compound is a chiral building block containing both an amino acid moiety and a heterocyclic thiophene ring. This molecule is primarily utilized in pharmaceutical research and development as a key chiral intermediate. Its main application lies in the synthesis of more complex bioactive molecules, particularly in the construction of peptidomimetics or as a component in the development of novel drug candidates. The thiophene ring can impart specific electronic and steric properties, potentially influencing the binding affinity and metabolic stability of the final compound. As a chiral amino acid derivative, it also finds use in biochemical and life science research for studying enzyme-substrate interactions, asymmetric synthesis, and as a precursor for specialized peptides. It is handled as a fine chemical under standard laboratory safety protocols.
    Physical Properties

    Boiling Point: 311.8 °C at 760 mmHg

    Flash Point: 142.4 °C

    Density: 1.418 g/cm3

    mg g kg ml l t