cis-2,6-dimethyl-morpholine, CAS No. 6485-55-8

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6485-55-8

Catalog No. EBD217475

CAS 6485-55-8

Name cis-2,6-dimethyl-morpholine

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Basic Information

Synonyms: cis-2,6-Dimethylmorphine Dimethylmorpholine cis-2,6-Dimethylmorpholine (2R,6S)-2,6-dimethylmorpholin-4-ium cis-2,6-dimethyl-morpholine (2R,6S)-2,6-dimethylmorpholine 2,6-cis-dimethylmorpholine cis2,6-dimethylmorpholine 2,6-dimethyl-morpholine (2R,6S)-2,6-Dimethyl-morpholine cis-(2s,6r)-dimethylmorpholine cis-(2r,6s)-2,6-dimethylmorpholine morpholine,2,6-dimethyl-,cis-(8ci)

Molecular Formula: C6H13NO

Molecular Weight: 115.17

MDL Number: MFCD00078428

Categories: Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

Cis-2,6-Dimethylmorpholine is a chiral heterocyclic amine featuring a morpholine ring with two methyl substituents in the cis configuration. Its structure combines a six-membered oxygen- and nitrogen-containing ring with defined stereochemistry, making it a valuable building block in organic synthesis. This compound is primarily utilized as a pharmaceutical intermediate, particularly in the synthesis of active pharmaceutical ingredients (APIs) targeting the central nervous system and metabolic disorders. Its morpholine core is a common pharmacophore in drug design, contributing to improved solubility and bioavailability. Additionally, it serves as a chiral auxiliary or resolving agent in asymmetric synthesis. As a secondary classification, it functions as a versatile synthetic building block in organic chemistry, enabling the construction of complex molecules via nucleophilic substitution or ring-opening reactions. It is typically handled under standard laboratory conditions with proper ventilation due to its amine-like odor and moderate reactivity.

Physical Properties

Melting Point: -85 °C

Boiling Point: 140-142 °C

Flash Point: 41 °C

Density: 0.93

Refractivity: 1.445-1.447

Storage: Flammables area

Analytical Data

Appearance: clear colorless liquid