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    6480-68-8

    Catalog No. EBD2223444

    CAS 6480-68-8

    Name Quinoline-3-carboxylicacid

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    Basic Information

    Synonyms: Quinoline-3-carboxylicacid 3-Quinolinecarboxylicacid quinoline-3-carboxylate

    Molecular Formula: C10H7NO2

    Molecular Weight: 173.17

    MDL Number: MFCD00006770

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters

    Product Description:
    Quinoline-3-carboxylic acid is an organic compound featuring a quinoline ring system substituted with a carboxylic acid group at the 3-position. It serves as a versatile and important heterocyclic building block in organic synthesis and medicinal chemistry. Its primary application is as a key intermediate in the synthesis of various pharmaceutical compounds. Notably, it is a crucial precursor in the production of certain antimalarial drugs and other bioactive molecules that incorporate the quinoline scaffold. The carboxylic acid group allows for further functionalization through amide bond formation or esterification, enabling the construction of more complex drug candidates. As a bifunctional molecule containing both a heterocyclic aromatic core and a reactive carboxylic acid, it is widely utilized in research and development for creating libraries of compounds with potential biological activity. It is commercially available from chemical suppliers specializing in fine chemicals and pharmaceutical intermediates.
    Physical Properties

    Melting Point: 277-280 °C(lit.)

    Boiling Point: 348.7 °C at 760 mmHg

    Flash Point: 164.7 °C

    Density: 1.339 g/cm3

    mg g kg ml l t