Tetracyclinehydrochloride CAS No.64-75-5 / Cat No.EBD2198184
Tetracycline Hydrochloride
[4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha)]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hydrochloride
Tetracycline hcl
(2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
(2E,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)
Tetracyclinehydrochloride
Tetracycline hcl
(2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
Properties
-
Appearance:
Yellow crystalline powder
-
Melting point:
220-223 °C(lit.)
-
Boiling point:
799.4 °C at 760 mmHg
-
Flashing point:
437.3 °C
-
Storage temperature:
−20°C
-
Coefficient of refraction:
-253 ° (C=0.5, 0.1mol/L HCl)
-
Optical rotation:
-252 º (c=0.5, H2O)
-
Solubility:
H2O: 10 mg/mL as a stock solution. Stock solutions should be filtered sterilized and stored at −20°C. Stable at 37°C for 4 days.
Safety Information
-
Symbol:
-
Signal words:
Warning -
Hazard statements:
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
-
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
NMR Spectrum
Prediction： H NMR (600 MHz, CD30D, hydrochloride) No. 7.50 (dd, 1H, J= 8.4,7.8 Hz, ArH), 7.13 (d, 1H, J = 7.8 Hz, ArH), 6.91 (d, 1 H, J = 8.4 Hz, ArH), 4.03 (s, 1H, CHN(CH3)2), 2.96-3.04 (m, 7H, HOC(CH3)CH, N(CH3)2), 2.91 (br dd, 1H, J= 12.6, 2.4 Hz, (CH3)2NCHCH), 2.18 (ddd, 1H, J= 12.6,6.0, 2.4 Hz, CHCHHCH), 1.90 (ddd, IH, J= 12.6, 12.6, 12.0 Hz, CHCHHCH), 1.60 (s, 3H, CH3)
1H NMR
13C NMR
