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    63593-03-3

    Catalog No. EBD545353

    CAS 63593-03-3

    Name 3-O-benzyl-4-C-hydroxymethyl-1,2-O-isopropylidene-±-D-erythro-pentofuranose

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    Basic Information

    Synonyms: 1,2-O-isopropylidene-3-O-benzyl-4-hydroxymethyl-±-D-ribofuranose a-D-erythro-Pentofuranose,4-C-(hydroxymethyl)-1,2-O-(1-methylethylidene)-3-O-(phenylmethyl)- [(3aR,6S,6aR)-6-(benzyloxy)-5-(hydroxymethyl)-2,2-dimethyl-tetrahydro-2H-furo[2,3-d][1,3]dioxol-5-yl]methanol

    Molecular Formula: C16H22O6

    Molecular Weight: 310.35

    Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides

    Product Description:
    3-O-Benzyl-4-C-hydroxymethyl-1,2-O-isopropylidene-ж┴-D-erythro-pentofuranose is a protected pentofuranose derivative featuring a benzyl ether at the 3-O position, a hydroxymethyl group at the 4-C position, and an isopropylidene acetal protecting the 1,2-diol. This compound serves as a key chiral building block in the synthesis of modified nucleosides and complex carbohydrates. Its rigid bicyclic structure and orthogonal protecting groups enable selective deprotection and functionalization, making it valuable for constructing C-nucleosides, locked nucleic acid (LNA) analogs, and other bioactive molecules. The compound is primarily utilized in medicinal chemistry research for developing antiviral and anticancer agents, as well as in carbohydrate chemistry for studying stereoselective transformations.
    Physical Properties
    mg g kg ml l t