3-Nitropyridin-2(1H)-one, CAS No. 6332-56-5

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6332-56-5

Catalog No. EBD216864

CAS 6332-56-5

Name 3-Nitropyridin-2(1H)-one

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Basic Information

Synonyms: 2-Hydroxy-3-nitropyridine 3-Nitro-2-Pyridinol 3-Nitro-2(1h)-Pyridone 3-Nitropyridin-2-Ol 3-Nitro-2-Pyridone 3-Nitro-2-Hydroxypyridine 3-Nitro-2(1h)-Pyridinone Aurora Ka-2996 2(3h)-Pyridinone,3-Nitro-(9ci) 2-Hydroxy-3-Nitro pyridine 3-nitropyridin-2(1H)-one 3-Nitro-2(1h)-Pyridone 3-Nitropyridin-2-Ol 3-Nitro-2-Pyridone 3-Nitro-2-Hydroxypyridine 3-Nitro-2(1h)-Pyridinone Aurora Ka-2996 2(3h)-Pyridinone,3-Nitro-(9ci) 2-Hydroxy-3-Nitro pyridine 3-nitropyridin-2(1H)-one 3-Nitropyridin-2(1H)-one

Molecular Formula: C5H4N2O3

Molecular Weight: 140.1

MDL Number: MFCD00006270

Categories: Synthetic Chemistry > Organic Building Blocks > Amines Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters Synthetic Chemistry > Organic Building Blocks > Phenols and Ethers

Product Description:

3-Nitropyridin-2(1H)-one is a heterocyclic compound featuring a pyridine ring with a nitro group at the 3-position and a keto-enol tautomeric system at the 2-position. It serves as a key building block in medicinal chemistry for the synthesis of various bioactive molecules, including kinase inhibitors and antimicrobial agents. The nitro group can be reduced to an amine for further functionalization, making it valuable in drug discovery. Additionally, it is utilized as a versatile synthetic intermediate in organic chemistry for constructing complex heterocyclic scaffolds.

Physical Properties

Melting Point: 212 °C (dec.)(lit.)

Boiling Point: 368.8 °C at 760 mmHg

Flash Point: 176.9 °C

Density: 1.44 g/cm3

Solubility: Insoluble in benzene, ether, petroleum ether and cold water, soluble in hot water, hot alcohol and dilute alkali

Analytical Data

Appearance: yellow needle-like crystal