(S)-3-Amino-1-N-Boc-piperidine, CAS No. 625471-18-3

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625471-18-3

Catalog No. EBD16446

CAS 625471-18-3

Name (S)-3-Amino-1-N-Boc-piperidine

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Basic Information

Synonyms: S-3-amino-1-N-Boc-piperidine (S)-1-Boc-3-piperidinamine (S)-1-BOC-3-AMINOPIPERIDINE (S)-3-Amino-1-N-Boc-piperidine S-1-N-Boc-3-AminoPiperidine tert-butyl(3S)-3-aminopiperidine-1-carboxylate

Molecular Formula: C10H20N2O2

Molecular Weight: 200.28

MDL Number: MFCD03094718

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

S-1-N-Boc-3-Aminopiperidine is a chiral piperidine derivative featuring a Boc-protected amino group at the 3-position. It serves as a crucial chiral building block and intermediate in pharmaceutical synthesis. The piperidine scaffold is a privileged structure found in numerous bioactive molecules. Its primary application is in the research and development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and other therapeutic agents. The chiral center and protected amine functionality make it a versatile precursor for constructing complex molecular architectures, enabling the synthesis of potential drug candidates with specific stereochemistry. As a Boc-protected amine, it offers stability during synthetic transformations and allows for selective deprotection under mild acidic conditions, facilitating further derivatization. This compound is a valuable tool in medicinal chemistry for exploring structure-activity relationships and optimizing drug-like properties.

Physical Properties

Boiling Point: 277.3 °C at 760 mmHg

Flash Point: 121.5 °C

Density: 1.041 g/cm3

Storage: Store under inert gas