(2R,3E)-4-Phenyl-3-buten-2-ol is a chiral, unsaturated secondary alcohol characterized by a phenyl group and a terminal double bond in conjugation with the alcohol-bearing carbon. Its molecular formula is C₁₀H₁₂O, and it exists as a specific stereoisomer with (R) configuration at the chiral center and an (E) configuration across the double bond. This structure makes it a valuable chiral building block in organic synthesis. The compound serves primarily as a versatile synthetic intermediate. The presence of both a stereogenic center and a reactive olefin moiety allows it to participate in various chemical transformations, such as oxidation to the corresponding aldehyde or ketone, further functionalization of the double bond (e.g., epoxidation, dihydroxylation, or cross-metathesis), and use in asymmetric synthesis. It is a key precursor in the synthesis of more complex chiral molecules, including potential pharmaceuticals and natural product analogs, where the defined stereochemistry is crucial for biological activity. As a specialized chiral synthon, it is typically used in research and development settings rather than in large-scale industrial applications. Handling requires standard precautions for organic compounds, including use in a well-ventilated area and avoidance of contact with strong oxidizers.