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    623950-02-7

    Catalog No. EBD607041

    CAS 623950-02-7

    Name 4'-carbamoyl N-Boc-2',6'-dimethyl-L-phenylalanine

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    Basic Information

    Synonyms: 4'-carbamoylN-Boc-2',6'-dimethyl-L-phenylalanine (S)-2-tert-butoxycarbonylamino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionicacid (S)-2-tert-Butoxycarbonylamino-3-(4-carbamoyl-2,6-dimethylphenyl)-propionicAcid (S)-2-tert-butoxycarbonylamino-3-(4-carbamoyl-2,6-dimethyl-phenyl)propionicacid (S)-2-tert-Butoxycarbonylamino-3-(4-carbamoyl-2,6-dimethylphenyl)propionicacid 4-(Aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine

    Molecular Formula: C17H24N2O5

    Molecular Weight: 336.39

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks Medicinal Chemistry > Biochemicals and Life Science Reagents > Peptides and Peptidomimetics

    Product Description:
    The compound with CAS number 623950-02-7 is a protected amino acid derivative, specifically 4-(aminocarbonyl)-N-[(1,1-dimethylethoxy)carbonyl]-2,6-dimethyl-L-phenylalanine. Its structure features an L-phenylalanine backbone with two methyl groups at the 2- and 6-positions of the aromatic ring, a carboxamide group at the 4-position, and a tert-butoxycarbonyl (Boc) protecting group on the alpha-amino group. This combination of a bulky, substituted aromatic side chain and a protected amine makes it a specialized, non-canonical amino acid building block. This compound is primarily used in the field of peptide chemistry and medicinal chemistry as a synthetic intermediate. The Boc-protected amine is a standard feature for solid-phase peptide synthesis (SPPS) using the Boc/Benzyl strategy, allowing for sequential peptide chain elongation. The unique dimethyl-substituted phenylalanine side chain is designed to impart specific steric, electronic, or conformational properties to the final peptide or peptidomimetic, potentially enhancing metabolic stability, receptor binding affinity, or altering pharmacokinetic profiles. It is therefore a key building block for constructing novel peptide-based drug candidates, probes, or biochemical tools. As a research chemical, it is handled under standard laboratory safety protocols. It is typically used by researchers in pharmaceutical development and chemical biology to explore structure-activity relationships and develop new therapeutic agents targeting various diseases, including those involving protein-protein interactions.
    Physical Properties

    Storage: −20°C

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