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    621-37-4

    Catalog No. EBD49533

    CAS 621-37-4

    Name 3-Hydroxyphenylacetic acid

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    Basic Information

    Synonyms: M-hydroxyphenylaceticacid (3-hydroxyphenyl)acetate 3-Hydroxyphenylaceticacid

    Molecular Formula: C8H8O3

    Molecular Weight: 152.15

    MDL Number: MFCD00004337

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Other Pharmaceutical Intermediates Synthetic Chemistry > Organic Building Blocks > Phenols and Ethers

    Product Description:
    3-Hydroxyphenylacetic acid is an organic compound featuring a phenyl ring substituted with a hydroxymethyl group at the meta position and a carboxylic acid group. It is a white to off-white crystalline powder. This compound serves as a versatile chemical intermediate, particularly in the pharmaceutical industry. It is a key building block in the synthesis of various active pharmaceutical ingredients (APIs). For instance, it is used in the production of certain beta-adrenergic blocking agents (beta-blockers) and other drug candidates. Its structure, containing both phenolic and carboxylic acid functionalities, allows for diverse chemical modifications, making it a valuable synthon in organic synthesis for constructing more complex molecules. As a bifunctional molecule, it is also employed in material science research and as a starting material for the synthesis of fine chemicals. Standard safety precautions for handling organic acids and phenols should be observed.
    Physical Properties

    Melting Point: 129-133 °C(lit.)

    Boiling Point: 349 °C at 760 mmHg

    Flash Point: 179.1 °C

    Density: 1.319 g/cm3

    Analytical Data

    Appearance: White Powder

    mg g kg ml l t