4-Hydrazinylbenzoic acid, CAS No. 619-67-0

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619-67-0

Catalog No. EBD18102

CAS 619-67-0

Name 4-Hydrazinylbenzoic acid

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Basic Information

Synonyms: 4-Hydrazinobenzoicacid 4-Hydrazinylbenzoicacid p-Hydrazinobenzoicacid 4-hydrazinobenzoate 4-hydrazinylbenzoate 4-carboxyphenylhydrazine p-carboxyphenylhydrazine (4-carboxyphenyl)hydrazine benzoicacid,4-hydrazino- benzoicacid,p-hydrazino- benzoicacid,4-hydrazino-(9ci) 4-carboxyphenylhydraziniumchloride p-hydrazinobenzoicacidhydrochloride 4-carboxyphenylhydrazinehydrochloride 4-hydrazinylbenzoicacidhydrochloride p-carboxyphenylhydrazinehydrochloride 4-hydrazinobenzoicacidmonohydrochloride

Molecular Formula: C7H8N2O2

Molecular Weight: 152.15

MDL Number: MFCD00007581

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Oximes and Hydrazones

Product Description:

4-Hydrazinobenzoic acid is an organic compound featuring both a benzoic acid group and a hydrazine substituent at the para position. This bifunctional structure makes it a versatile building block in synthetic chemistry. Its primary and most significant application is as a key pharmaceutical intermediate. It serves as a crucial precursor in the synthesis of various heterocyclic compounds, particularly pyrazole and pyrazolone derivatives. These heterocyclic scaffolds are found in numerous active pharmaceutical ingredients (APIs) with diverse therapeutic activities, including anti-inflammatory and analgesic agents. The compound is also utilized in the preparation of azo dyes and pigments due to its diazotization capability. As a reagent, it is employed in organic synthesis for the formation of hydrazones and other functional groups. Standard safety precautions for handling hydrazine derivatives should be observed due to potential toxicity.

Physical Properties

Melting Point: 218 °C (dec.)(lit.)

Boiling Point: 377.2 °C at 760 mmHg

Flash Point: 181.9 °C

Density: 1.401 g/cm3

Analytical Data

Appearance: solid