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    619-56-7

    Catalog No. EBD31562

    CAS 619-56-7

    Name 4-Chlorobenzamide

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    Basic Information

    Synonyms: 4-Chlorobenzamide p-chlorobenzamide p-chlorobenzoicacidamide

    Molecular Formula: C7H6ClNO

    Molecular Weight: 155.58

    MDL Number: MFCD00007993

    Categories: Synthetic Chemistry > Organic Building Blocks > Amines Medicinal Chemistry > Pharmaceutical Intermediates > Drug Synthesis Building Blocks

    Product Description:
    4-Chlorobenzamide is an organic compound with the molecular formula C7H6ClNO. It is a white to off-white crystalline solid characterized by a benzamide core structure substituted with a chlorine atom at the para position. This compound serves as a versatile and fundamental building block in organic synthesis. Its primary application is as a key synthetic intermediate in the pharmaceutical industry. It is notably used in the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates. For instance, it is a crucial precursor in the production of benzodiazepine derivatives, which are a class of psychoactive drugs. Additionally, it finds use in the synthesis of herbicides and other agrochemicals, as well as in materials science for creating polymers and liquid crystals. As a bifunctional molecule containing both an amide and an aryl chloride group, 4-chlorobenzamide participates in a range of chemical transformations, including nucleophilic aromatic substitution and further functionalization of the amide moiety. It is commercially available from major chemical suppliers for research and development purposes.
    Physical Properties

    Melting Point: 172-176 °C(lit.)

    Boiling Point: 290.2 °C at 760 mmHg

    Flash Point: 129.3 °C

    Density: 1.295 g/cm3

    Solubility: slightly soluble

    Analytical Data

    Appearance: white powder

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