α-D-Mannopyranoside, methyl, CAS No. 617-04-9

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617-04-9

Catalog No. EBD2217102

CAS 617-04-9

Name α-D-Mannopyranoside, methyl

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Basic Information

Synonyms: α-D-Mannopyranoside,methyl Methyl-alpha-D-mannopyranoside Methylalpha-D-mannopyranoside 1-O-Methyl-alpha-D-mannopyranoside Methylalpha-D-mannoside(VAN) NSC1225 alpha-D-Methylmannoside alpha-Methylmannopyranoside alpha-Methyl-D-(-)-mannoside Mannopyranoside,methyl,alpha-D- alpha-D-Mannopyranoside,methyl methylbeta-L-galactopyranoside methylbeta-L-glucopyranoside methylalpha-L-galactopyranoside methylbeta-L-talopyranoside methylalpha-L-talopyranoside 2-O-methyl-alpha-D-mannopyranose Methylα-D-mannopyranoside mmpsupplement 1-ome-alpha-d-man -d-mannopyranoside -methyld-mannoside 1-o-methyl-mannoside a-methyl-d-mannoside alpha-methylmannoside d-(+)-methylmannoside alpha-methyl-d-mannoside methylalpha-d-mannoside methyl-a-d-mannopyranoside alpha-methyl-d-mannopyranoside .alpha.-d-mannopyranoside,methyl methylalpha-d-mannopyranosidesupplement*

Molecular Formula: C7H14O6

Molecular Weight: 194.18

MDL Number: MFCD00063262

Categories: Medicinal Chemistry > Biochemicals and Life Science Reagents > Saccharides, Nucleosides, and Nucleotides Synthetic Chemistry > Organic Building Blocks > Other Organic Building Blocks

Product Description:

Methyl α-D-mannopyranoside is a synthetic derivative of D-mannose, where the anomeric hydroxyl group is methylated. It is a white crystalline solid with the molecular formula C7H14O6 and is commonly used as a specific inhibitor of lectins, particularly concanavalin A (ConA), due to its high affinity for the mannose-binding site. Its primary application is in biochemical and biomedical research as a tool compound. It is extensively used in lectin affinity chromatography for the purification and isolation of glycoproteins and in cell biology studies to probe carbohydrate-protein interactions on cell surfaces. It also serves as a valuable starting material or intermediate in the chemical and enzymatic synthesis of more complex oligosaccharides, glycoconjugates, and glycomimetics for drug discovery. While not a therapeutic agent itself, its role in fundamental glycoscience research and as a building block for synthesizing bioactive carbohydrate derivatives places it firmly within the realm of life science reagents and specialized synthetic blocks.

Physical Properties

Melting Point: 193-196 °C(lit.)

Boiling Point: 389.1 °C at 760 mmHg

Flash Point: 189.1 °C

Density: 1.47 g/cm3

Solubility: H2O: 0.1 g/mL, clear

Refractivity: 79.5 ° (C=4, H2O)