2-Iodoaniline, CAS No. 615-43-0

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615-43-0

Catalog No. EBD24814

CAS 615-43-0

Name 2-Iodoaniline

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Basic Information

Synonyms: AI3-00493 Aniline,2-iodo- Aniline,o-iodo- NSC34544 o-Aminoiodobenzene o-Iodoaniline Benzenamine,2-iodo- 1-Amino-2-iodobenzene 2-Iodoaniline

Molecular Formula: C6H6IN

Molecular Weight: 219.02

MDL Number: MFCD00007680

Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

2-Iodoaniline is an organic compound featuring both an amine (-NH2) and an iodine substituent on a benzene ring. It is a pale yellow to brown crystalline solid or powder. This bifunctional molecule is a versatile building block in organic synthesis. Its primary application is as a key intermediate in the synthesis of more complex molecules. The iodine atom is an excellent site for cross-coupling reactions, such as Suzuki, Stille, or Buchwald-Hartwig amination, allowing for the introduction of various aryl, alkenyl, or amino groups. The aniline moiety can be further functionalized through diazotization, acylation, or alkylation. It is used in the preparation of pharmaceuticals, agrochemicals, and functional materials like dyes and liquid crystals. The compound should be handled with care as it is toxic and may cause skin and eye irritation. It is sensitive to light and air, often requiring storage under inert atmosphere and refrigeration.

Physical Properties

Melting Point: 55-58 °C(lit.)

Boiling Point: 262 °C at 760 mmHg

Flash Point: 113 °C

Density: 1.924 g/cm3

Analytical Data

Appearance: yellow to brown crystalline needles