Chalcone is an α,β-unsaturated ketone characterized by its core structure of two aromatic rings linked by a three-carbon α,β-unsaturated carbonyl system. It serves as a fundamental scaffold in organic synthesis and materials science. Its primary industrial and research significance lies in the field of optoelectronics. Chalcone and its numerous derivatives are extensively studied as key precursors and active components in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and non-linear optical (NLO) materials. Their conjugated structure allows for tunable photophysical properties, making them valuable for designing charge-transporting layers, emissive materials, and light-harvesting molecules. Due to its simple yet versatile structure, chalcone is also a classic and widely used organic synthesis building block. It is commonly employed in heterocyclic synthesis (e.g., pyrazolines, flavones) via cyclization reactions and serves as a Michael acceptor in conjugate addition reactions, making it a staple reagent in synthetic chemistry laboratories.