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    61367-22-4

    Catalog No. EBD1006160

    CAS 61367-22-4

    Name (cis-4-Aminocyclohexyl)methanol hydrochloride

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    Basic Information

    Synonyms: cis-4-aminocyclohexanemethanolhydrochloride (cis-4-Aminocyclohexyl)methanolhydrochloride (cis-4-Aminocyclohexyl)methanolhydrochloride(1:1)

    Molecular Formula: C7H15NO*ClH

    Molecular Weight: 165.66

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Chiral Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    (cis-4-Aminocyclohexyl)methanol hydrochloride is a chiral organic compound featuring both an amino group and a hydroxymethyl group on a cyclohexane ring in a cis configuration. It is commonly supplied as a hydrochloride salt to enhance stability and handling properties. This compound serves as a crucial chiral building block in pharmaceutical synthesis. Its primary application is in the development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. For instance, it is a key intermediate in the synthesis of Pregabalin, a widely prescribed medication for neuropathic pain, fibromyalgia, and certain types of seizures. The cis-aminocyclohexylmethanol scaffold provides a rigid, conformationally defined structure that is valuable for designing molecules with specific biological activity. As a bifunctional synthon containing both nucleophilic (amine) and nucleophilic/leaving group (alcohol) handles, it is a versatile intermediate in organic chemistry. It enables the construction of more complex molecular architectures through further functionalization, such as amide bond formation or etherification.
    Physical Properties
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