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    61047-43-6

    Catalog No. EBD24891

    CAS 61047-43-6

    Name 8-Bromo-2-methylquinoline

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    Basic Information

    Synonyms: 8-Bromo-2-methylquinoline quinoline,8-bromo-2-methyl- 8-BROMO-2-METHYL-QUINOLINE 2-Methyl-8-bromoquinoline

    Molecular Formula: C10H8BrN

    Molecular Weight: 222.08

    MDL Number: MFCD04966997

    Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds

    Product Description:
    8-Bromo-2-methylquinoline is an organic compound featuring a quinoline core substituted with a bromine atom at the 8-position and a methyl group at the 2-position. It is a pale yellow to brown solid or crystalline powder with a molecular formula of C10H8BrN and a molecular weight of 222.08 g/mol. This compound is primarily utilized as a versatile building block in medicinal chemistry and pharmaceutical research. Its structure serves as a key intermediate in the synthesis of various biologically active molecules, particularly those targeting neurological and anti-infective pathways. The bromine atom at the 8-position provides a reactive handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Stille), enabling the construction of more complex quinoline derivatives for drug discovery. As a halogenated heterocycle, it is also a valuable reagent in organic synthesis for constructing fused ring systems and functionalized quinolines. Standard safety precautions for handling brominated aromatic compounds should be observed, including the use of personal protective equipment.
    Physical Properties

    Boiling Point: 299.7°C at 760 mmHg

    Flash Point: 135°C

    Density: 1.488g/cm3

    mg g kg ml l t