Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

    OK
    Get Quote Login
    6000-00-6

    Catalog No. EBD2860822

    CAS 6000-00-6

    Name (2E)- 4-bromo-2-Butenoic acid methyl ester

    Get Quote
    Basic Information

    Synonyms: (2E)-4-bromo-2-Butenoicacidmethylester methyltrans-4-bromo-2-butenoate

    Molecular Formula: C5H7BrO2

    Molecular Weight: 179.01

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > C-C Double and Triple Bonds

    Product Description:
    Methyl 4-bromo-2-butenoate is an organic compound featuring both an α,β-unsaturated ester moiety and an allylic bromide functional group. This bifunctional structure makes it a versatile and reactive building block in synthetic organic chemistry. Its primary application is as a key intermediate in the synthesis of more complex molecules. The allylic bromide site is highly reactive in nucleophilic substitution reactions (e.g., SN2), allowing for the introduction of various nucleophiles. Simultaneously, the α,β-unsaturated ester is an excellent Michael acceptor, enabling conjugate addition reactions. This dual reactivity is exploited in multi-step syntheses, particularly for constructing carbon chains and heterocyclic systems. Due to its reactive nature, it should be handled with care under inert atmosphere and stored at low temperatures. It is a valuable reagent for academic and industrial research laboratories focused on developing new synthetic methodologies and preparing pharmaceutical or agrochemical intermediates.
    Physical Properties

    Boiling Point: 70 °C/0.03 mmHg(lit.)

    Flash Point: 92 °C

    Density: 1.498 g/mL at 20 °C(lit.)

    Refractivity: n20/D 1.501

    Storage: 2-8°C

    mg g kg ml l t