3-Amino-2-naphthoic acid, CAS No. 5959-52-4

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5959-52-4

Catalog No. EBD32172

CAS 5959-52-4

Name 3-Amino-2-naphthoic acid

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Basic Information

Synonyms: 2-Amino-3-carboxynaphthalene 2-Amino-3-naphthoicacid 3-14-00-01341(BeilsteinHandbookReference) 3-Amino-2-naphthalenecarboxylicacid 3-Aminoisonaphthoicacid BRN0744099 NSC37061 2-Naphthalenecarboxylicacid,3-amino- 2-Naphthoicacid,3-amino- 3-aminonaphthalene-2-carboxylicacid 3-aminonaphthalene-2-carboxylate 3-Amino-2-naphthoicacid

Molecular Formula: C11H9NO2

Molecular Weight: 187.19

MDL Number: MFCD00004115

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

3-Amino-2-naphthoic acid is an organic compound featuring both an amino group and a carboxylic acid group on a naphthalene ring system. This bifunctional structure makes it a versatile building block in synthetic chemistry. Its primary application is as a key pharmaceutical intermediate. It serves as a crucial precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), most notably naphthypramide. The compound's structure allows for further derivatization to create molecules with targeted biological activity. Beyond its pharmaceutical use, it is employed in the synthesis of various organic dyes and pigments due to the naphthalene core's ability to contribute to color and fluorescence properties. It is also utilized in materials science research. As a solid, it requires careful handling to avoid inhalation and contact.

Physical Properties

Melting Point: 212-215 °C (dec.)(lit.)

Boiling Point: 384.9 °C at 760 mmHg

Flash Point: 186.6 °C

Density: 1.352 g/cm3

Analytical Data

Appearance: yellow-green to green powder