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    595-46-0

    Catalog No. EBD49866

    CAS 595-46-0

    Name Dimethylmalonic acid

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    Basic Information

    Synonyms: dimethylmalonicacid dimethylpropanedioicacid 2,2-Dimethyl-malonicacid Dimethyl-propanedioicacid

    Molecular Formula: C5H8O4

    Molecular Weight: 132.11

    MDL Number: MFCD00004193

    Categories: Synthetic Chemistry > Organic Building Blocks > Carboxylic Acids and Esters Synthetic Chemistry > Basic Synthetic Reagents > Other Basic Synthetic Reagents

    Product Description:
    Dimethylmalonic acid is a dicarboxylic acid derivative with the molecular formula C5H8O4. It is a white to off-white crystalline powder. The compound features two carboxylic acid groups and a central carbon atom bearing two methyl groups, making it a versatile and symmetrical building block in organic synthesis. Its primary application is as a key intermediate in the synthesis of various pharmaceuticals and fine chemicals. For instance, it serves as a crucial precursor in the production of certain barbiturates and other heterocyclic compounds. The molecule is also employed in the synthesis of polymers and as a starting material for preparing other malonic acid derivatives through decarboxylation or further functionalization reactions. Due to its structure, it is a valuable reagent for introducing the malonate moiety or for C-C bond formation via its diesters. As a bifunctional acid, it requires careful handling. It is typically stored in a cool, dry place and should be kept away from strong oxidizing agents and bases.
    Physical Properties

    Melting Point: 191-193 °C(lit.)

    Boiling Point: 310.199 °C at 760 mmHg

    Flash Point: 155.625 °C

    Density: 1.316 g/cm3

    Analytical Data

    Appearance: White to off-white crystal

    mg g kg ml l t