2-amino-5-chlorobenzonitrile, CAS No. 5922-60-1

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

5922-60-1

Catalog No. EBD1955799

CAS 5922-60-1

Name 2-amino-5-chlorobenzonitrile

Get Quote

Basic Information

Synonyms: 2-amino-5-chlorobenzonitrile AMINO(2-)5-CHLORO-BENZONITRILE ACBN TIMTEC-BBSBB004050 2-amino-5-chloro-benzonitril 4-Chloro-2-cyanoaniline 2-AMINO-5-CHLORBENZOESAEURENITRIL

Molecular Formula: C7H5ClN2

Molecular Weight: 152.58

MDL Number: MFCD00017106

Categories: Medicinal Chemistry > Pharmaceutical Intermediates > Heterocyclic Intermediates Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

2-Amino-5-chlorobenzonitrile is an organic compound featuring both an amino group and a cyano group attached to a chlorinated benzene ring. It serves as a versatile and important aromatic amine building block in synthetic chemistry. Its primary and most significant application is as a key pharmaceutical intermediate. It is notably used in the synthesis of benzodiazepine derivatives, a major class of psychoactive drugs. For instance, it is a crucial precursor in the production of Clonazepam, a potent anticonvulsant and anxiolytic medication. The molecule's structure allows for further functionalization, making it valuable for constructing complex heterocyclic systems central to many drug discovery programs. Beyond its pharmaceutical role, this compound is also employed in the synthesis of dyes, pigments, and other fine chemicals. As a bifunctional reagent (containing amine and nitrile groups), it is a useful starting material in organic research for constructing more complex molecular architectures.

Physical Properties

Melting Point: 96-99 °C(lit.)

Boiling Point: 132-135 °C/0.5 mmHg(lit.)

Flash Point: 113 °C

Density: 1.33 g/cm3

Analytical Data

Appearance: white to light beige crystalline needles