N-((tert-Butoxycarbonyl)oxy)benzimidoyl cyanide, CAS No. 58632-95-4

Welcome to iChemical.com!

In the below part, please select the country you want us to ship to: Please note that once you've selected a shipping country, all pricing information on our website will be automatically updated to include door-to-door shipping to the country you specified.

North America

South America

Africa

Europe

Asia

Oceania

58632-95-4

Catalog No. EBD953

CAS 58632-95-4

Name N-((tert-Butoxycarbonyl)oxy)benzimidoyl cyanide

Get Quote

Basic Information

Synonyms: N-((tert-Butoxycarbonyl)oxy)benzimidoylcyanide BOC-ON 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile BOC-ON(2-t-butoxycarbonyloxyimino)-2-phenylacetonitirle) 2-(Boc-oxyimino)-2-phenylacetonitrile~2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile N-T-butoxycarbonyloxyimino-2-*phenylacetonitrile {[(tert-butoxycarbonyl)oxy]imino}(phenyl)acetonitrile (2Z)-{[(tert-butoxycarbonyl)oxy]imino}(phenyl)ethanenitrile (2E)-{[(tert-butoxycarbonyl)oxy]imino}(phenyl)ethanenitrile

Molecular Formula: C13H14N2O2

Molecular Weight: 230.26

MDL Number: MFCD00001863

Categories: Synthetic Chemistry > Organic Building Blocks > Cyano Compounds Synthetic Chemistry > Organic Building Blocks > Amines

Product Description:

2-(tert-Butoxycarbonylamino)-2-phenylacetonitrile is a versatile organic building block characterized by a phenylacetonitrile core substituted with a tert-butoxycarbonyl (Boc) protected amino group at the alpha position. This structure combines a nitrile functionality, a protected amine, and an aromatic ring, making it a valuable precursor for the synthesis of more complex molecules. Its primary application is in organic synthesis, particularly in medicinal chemistry and peptide mimetics research. The nitrile group can be transformed into various other functional groups, such as carboxylic acids, amides, or tetrazoles. The Boc-protected alpha-amino group is crucial for the controlled introduction of amino acid-like moieties, enabling the construction of non-natural amino acids, dipeptide analogs, and other pharmacologically relevant scaffolds. It serves as a key intermediate in the synthesis of compounds with potential biological activity. This compound is typically handled under standard laboratory conditions for air- and moisture-sensitive materials. Its utility lies in its role as a bifunctional synthon, allowing for sequential and selective chemical modifications to access diverse chemical libraries for drug discovery and material science applications.

Physical Properties

Melting Point: 85-88 °C(lit.)

Boiling Point: 324.1 °C at 760 mmHg

Flash Point: 149.8 °C

Density: 1.08 g/cm3

Solubility: insoluble

Storage: −20°C

Analytical Data

Appearance: White to off-white microcrystalline powder