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    5847-59-6

    Catalog No. EBD12972

    CAS 5847-59-6

    Name 2-Bromo-4-nitrophenol

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    Basic Information

    Synonyms: Phenol,2-bromo-4-nitro-(8CI)(9CI) NSC212120 2-Bromo-4-nitrophenol

    Molecular Formula: C6H4BrNO3

    Molecular Weight: 218.0

    MDL Number: MFCD06656567

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Phenols and Ethers

    Product Description:
    2-Bromo-4-nitrophenol is an organic compound featuring both a bromine atom and a nitro group attached to a phenol ring. It is a yellow to orange crystalline solid with a molecular formula of C6H4BrNO3. This compound is a versatile bifunctional building block in organic synthesis, where the bromine atom serves as a site for cross-coupling reactions (e.g., Suzuki, Heck reactions) and the nitro group can be reduced to an amine or participate in other transformations. Its primary application is as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. For example, it is used in the preparation of benzimidazole derivatives and other heterocyclic compounds with potential biological activity. The presence of both electron-withdrawing groups makes it a useful precursor for constructing molecules with specific electronic properties. The compound requires careful handling due to its potential irritant properties. It is typically stored in a cool, dry place away from strong oxidizing agents.
    Physical Properties

    Melting Point: 111-115 °C

    Boiling Point: 298.1 °C at 760 mmHg

    Flash Point: 134.1 °C

    Density: 1.881 g/cm3

    Safety Information

    Packing Level: III

    Hazard Category: 9

    Transport Codes: 3077

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