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    58401-43-7

    Catalog No. EBD2201054

    CAS 58401-43-7

    Name 3-Amino-4-chloroquinoline

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    Basic Information

    Synonyms: 3-Amino-4-chloroquinoline 3-Quinolinamine,4-chloro-

    Molecular Formula: C9H7ClN2

    Molecular Weight: 178.62

    Categories: Synthetic Chemistry > Organic Building Blocks > Halogenated Compounds Synthetic Chemistry > Organic Building Blocks > Amines

    Product Description:
    3-Amino-4-chloroquinoline is a heterocyclic building block featuring a quinoline core substituted with an amino group at the 3-position and a chlorine atom at the 4-position. Its molecular formula is C9H7ClN2, and it serves as a key intermediate in medicinal chemistry. This compound is primarily utilized in the synthesis of pharmaceutical agents, particularly those targeting infectious diseases and cancer. The 4-chloro substituent is a versatile handle for nucleophilic aromatic substitution, enabling the introduction of various side chains to modulate biological activity. It is a common precursor for developing antimalarial, antibacterial, and antiviral drug candidates. As a bifunctional molecule, it also functions as a general synthetic building block in organic chemistry. The amino group allows for further derivatization via acylation or alkylation, making it valuable for constructing diverse nitrogen-containing heterocycles and complex molecular libraries in drug discovery.
    Physical Properties
    mg g kg ml l t